Dart VM flags and options can be provided to any executable generated using dart compile exe via the DART_VM_OPTIONS environment variable.
DART_VM_OPTIONS should be set to a list of comma-separated flags and options with no whitespace. Options that allow for multiple values to be provided as comma-separated values are not supported (e.g., --timeline-streams=Dart,GC,Compiler).
Example of a valid DART_VM_OPTIONS environment variable:
DART_VM_OPTIONS=--random_seed=42,--verbose_gc