diff --git a/CHANGELOG.md b/CHANGELOG.md
index b4c038a..fbba72b 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,4 +1,11 @@
-## 2.16.0
+## 2.16.1 - 2022-02-09
+
+This is a patch release that fixes an AOT precompiler crash when building some
+Flutter apps (issue [flutter/flutter#97301][]).
+
+[flutter/flutter#97301]: https://github.com/flutter/flutter/issues/97301
+
+## 2.16.0 - 2022-02-03
 
 ### Core libraries
 
diff --git a/runtime/vm/compiler/frontend/kernel_to_il.cc b/runtime/vm/compiler/frontend/kernel_to_il.cc
index dba179a..ad2628a 100644
--- a/runtime/vm/compiler/frontend/kernel_to_il.cc
+++ b/runtime/vm/compiler/frontend/kernel_to_il.cc
@@ -1585,7 +1585,8 @@
       // Initialize the result's data pointer field.
       body += LoadLocal(typed_data_object);
       body += LoadLocal(arg_pointer);
-      body += LoadNativeField(Slot::Pointer_data_field());
+      body += LoadUntagged(compiler::target::Pointer::data_field_offset());
+      body += ConvertUntaggedToUnboxed(kUnboxedIntPtr);
       body += StoreNativeField(Slot::TypedDataBase_data_field(),
                                StoreInstanceFieldInstr::Kind::kInitializing,
                                kNoStoreBarrier);
diff --git a/tests/ffi/regress_flutter97301_test.dart b/tests/ffi/regress_flutter97301_test.dart
new file mode 100644
index 0000000..c330d70
--- /dev/null
+++ b/tests/ffi/regress_flutter97301_test.dart
@@ -0,0 +1,21 @@
+// Copyright (c) 2022, the Dart project authors.  Please see the AUTHORS file
+// for details. All rights reserved. Use of this source code is governed by a
+// BSD-style license that can be found in the LICENSE file.
+//
+// Verifies that there are no deoptimizing IntConverter instructions
+// used when converting Pointer to TypedData.
+// Regression test for https://github.com/flutter/flutter/issues/97301.
+
+import "dart:ffi";
+import "package:ffi/ffi.dart";
+
+@pragma("vm:never-inline")
+Pointer<Uint32> foo() => calloc(4);
+
+main() {
+  final Pointer<Uint32> offsetsPtr = foo();
+
+  for (var i = 0; i < 2; i++) {
+    print(offsetsPtr.asTypedList(1));
+  }
+}
diff --git a/tests/ffi_2/regress_flutter97301_test.dart b/tests/ffi_2/regress_flutter97301_test.dart
new file mode 100644
index 0000000..1417a7a
--- /dev/null
+++ b/tests/ffi_2/regress_flutter97301_test.dart
@@ -0,0 +1,23 @@
+// Copyright (c) 2022, the Dart project authors.  Please see the AUTHORS file
+// for details. All rights reserved. Use of this source code is governed by a
+// BSD-style license that can be found in the LICENSE file.
+//
+// Verifies that there are no deoptimizing IntConverter instructions
+// used when converting Pointer to TypedData.
+// Regression test for https://github.com/flutter/flutter/issues/97301.
+
+// @dart = 2.9
+
+import "dart:ffi";
+import "package:ffi/ffi.dart";
+
+@pragma("vm:never-inline")
+Pointer<Uint32> foo() => calloc(4);
+
+main() {
+  final Pointer<Uint32> offsetsPtr = foo();
+
+  for (var i = 0; i < 2; i++) {
+    print(offsetsPtr.asTypedList(1));
+  }
+}
diff --git a/tools/VERSION b/tools/VERSION
index b022ca2..9be6324 100644
--- a/tools/VERSION
+++ b/tools/VERSION
@@ -26,6 +26,6 @@
 CHANNEL stable
 MAJOR 2
 MINOR 16
-PATCH 0
+PATCH 1
 PRERELEASE 0
 PRERELEASE_PATCH 0
\ No newline at end of file