diff --git a/CHANGELOG.md b/CHANGELOG.md
index 70414c2..a5313a2 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -63,6 +63,10 @@
 - Deprecate `SecureSocket.renegotiate` and `RawSecureSocket.renegotiate`,
   which were no-ops.
 
+#### `dart:isolate`
+
+- Add `Isolate.run` to run a function in a new isolate.
+
 ### Tools
 
 #### Dart command line
diff --git a/sdk/lib/isolate/isolate.dart b/sdk/lib/isolate/isolate.dart
index 48c046f..517beee 100644
--- a/sdk/lib/isolate/isolate.dart
+++ b/sdk/lib/isolate/isolate.dart
@@ -144,6 +144,106 @@
   /// inspect the isolate and see uncaught errors or when it terminates.
   Isolate(this.controlPort, {this.pauseCapability, this.terminateCapability});
 
+  /// Runs [computation] in a new isolate and returns the result.
+  ///
+  /// ```dart
+  /// int slowFib(int n) =>
+  ///     n <= 1 ? 1 : slowFib(n - 1) + slowFib(n - 2);
+  ///
+  /// // Compute without blocking current isolate.
+  /// var fib40 = await Isolate.run(() => slowFib(40));
+  /// ```
+  ///
+  /// If [computation] is asynchronous (returns a `Future<R>`) then
+  /// that future is awaited in the new isolate, completing the entire
+  /// asynchronous computation, before returning the result.
+  ///
+  /// ```dart
+  /// int slowFib(int n) =>
+  ///     n <= 1 ? 1 : slowFib(n - 1) + slowFib(n - 2);
+  /// Stream<int> fibStream() async* {
+  ///   for (var i = 0;; i++) yield slowFib(i);
+  /// }
+  ///
+  /// // Returns `Future<int>`.
+  /// var fib40 = await Isolate.run(() => fibStream().elementAt(40));
+  /// ```
+  ///
+  /// If [computation] throws, the isolate is terminated and this
+  /// function throws the same error.
+  ///
+  /// ```dart import:convert
+  /// Future<int> eventualError() async {
+  ///   await Future.delayed(const Duration(seconds: 1));
+  ///   throw StateError("In a bad state!");
+  /// }
+  ///
+  /// try {
+  ///   await Isolate.run(eventualError);
+  /// } on StateError catch (e, s) {
+  ///   print(e.message); // In a bad state!
+  ///   print(LineSplitter.split("$s").first); // Contains "eventualError"
+  /// }
+  /// ```
+  /// Any uncaught asynchronous errors will terminate the computation as well,
+  /// but will be reported as a [RemoteError] because [addErrorListener]
+  /// does not provide the original error object.
+  ///
+  /// The result is sent using [exit], which means it's sent to this
+  /// isolate without copying.
+  ///
+  /// The [computation] function and its result (or error) must be
+  /// sendable between isolates.
+  ///
+  /// The [debugName] is only used to name the new isolate for debugging.
+  @Since("2.17")
+  static Future<R> run<R>(FutureOr<R> computation(), {String? debugName}) {
+    var result = Completer<R>();
+    var resultPort = RawReceivePort();
+    resultPort.handler = (response) {
+      resultPort.close();
+      if (response == null) {
+        // onExit handler message, isolate terminated without sending result.
+        result.completeError(
+            RemoteError("Computation ended without result", ""),
+            StackTrace.empty);
+        return;
+      }
+      var list = response as List<Object?>;
+      if (list.length == 2) {
+        var remoteError = list[0];
+        var remoteStack = list[1];
+        if (remoteStack is StackTrace) {
+          // Typed error.
+          result.completeError(remoteError!, remoteStack);
+        } else {
+          // onError handler message, uncaught async error.
+          // Both values are strings, so calling `toString` is efficient.
+          var error =
+              RemoteError(remoteError.toString(), remoteStack.toString());
+          result.completeError(error, error.stackTrace);
+        }
+      } else {
+        assert(list.length == 1);
+        result.complete(list[0] as R);
+      }
+    };
+    try {
+      Isolate.spawn(_RemoteRunner._remoteExecute,
+              _RemoteRunner<R>(computation, resultPort.sendPort),
+              onError: resultPort.sendPort,
+              onExit: resultPort.sendPort,
+              errorsAreFatal: true,
+              debugName: debugName)
+          .then<void>((_) {}, onError: result.completeError);
+    } on Object {
+      // Sending the computation failed.
+      resultPort.close();
+      rethrow;
+    }
+    return result.future;
+  }
+
   /// An [Isolate] object representing the current isolate.
   ///
   /// The current isolate for code using [current]
@@ -345,7 +445,7 @@
   /// of the isolate identified by [controlPort],
   /// the pause request is ignored by the receiving isolate.
   Capability pause([Capability? resumeCapability]) {
-    resumeCapability ??= new Capability();
+    resumeCapability ??= Capability();
     _pause(resumeCapability);
     return resumeCapability;
   }
@@ -533,12 +633,12 @@
       var listMessage = message as List<Object?>;
       var errorDescription = listMessage[0] as String;
       var stackDescription = listMessage[1] as String;
-      var error = new RemoteError(errorDescription, stackDescription);
+      var error = RemoteError(errorDescription, stackDescription);
       controller.addError(error, error.stackTrace);
     }
 
     controller.onListen = () {
-      RawReceivePort receivePort = new RawReceivePort(handleError);
+      RawReceivePort receivePort = RawReceivePort(handleError);
       port = receivePort;
       this.addErrorListener(receivePort.sendPort);
     };
@@ -765,7 +865,7 @@
   final StackTrace stackTrace;
   RemoteError(String description, String stackDescription)
       : _description = description,
-        stackTrace = new StackTrace.fromString(stackDescription);
+        stackTrace = StackTrace.fromString(stackDescription);
   String toString() => _description;
 }
 
@@ -795,3 +895,62 @@
   /// transferable bytes, even if the calls occur in different isolates.
   ByteBuffer materialize();
 }
+
+/// Parameter object used by [Isolate.run].
+///
+/// The [_remoteExecute] function is run in a new isolate with a
+/// [_RemoteRunner] object as argument.
+class _RemoteRunner<R> {
+  /// User computation to run.
+  final FutureOr<R> Function() computation;
+
+  /// Port to send isolate computation result on.
+  ///
+  /// Only one object is ever sent on this port.
+  /// If the value is `null`, it is sent by the isolate's "on-exit" handler
+  /// when the isolate terminates without otherwise sending value.
+  /// If the value is a list with one element,
+  /// then it is the result value of the computation.
+  /// Otherwise it is a list with two elements representing an error.
+  /// If the error is sent by the isolate's "on-error" uncaught error handler,
+  /// then the list contains two strings. This also terminates the isolate.
+  /// If sent manually by this class, after capturing the error,
+  /// the list contains one non-`null` [Object] and one [StackTrace].
+  final SendPort resultPort;
+
+  _RemoteRunner(this.computation, this.resultPort);
+
+  /// Run in a new isolate to get the result of [computation].
+  ///
+  /// The result is sent back on [resultPort] as a single-element list.
+  /// A two-element list sent on the same port is an error result.
+  /// When sent by this function, it's always an object and a [StackTrace].
+  /// (The same port listens on uncaught errors from the isolate, which
+  /// sends two-element lists containing [String]s instead).
+  static void _remoteExecute(_RemoteRunner<Object?> runner) {
+    runner._run();
+  }
+
+  void _run() async {
+    R result;
+    try {
+      var potentiallyAsyncResult = computation();
+      if (potentiallyAsyncResult is Future<R>) {
+        result = await potentiallyAsyncResult;
+      } else {
+        result = potentiallyAsyncResult as R;
+      }
+    } catch (e, s) {
+      // If sending fails, the error becomes an uncaught error.
+      Isolate.exit(resultPort, _list2(e, s));
+    }
+    Isolate.exit(resultPort, _list1(result));
+  }
+
+  /// Helper function to create a one-element non-growable list.
+  static List<Object?> _list1(Object? value) => List.filled(1, value);
+
+  /// Helper function to create a two-element non-growable list.
+  static List<Object?> _list2(Object? value1, Object? value2) =>
+      List.filled(2, value1)..[1] = value2;
+}
diff --git a/tests/lib/isolate/isolate_run_test.dart b/tests/lib/isolate/isolate_run_test.dart
new file mode 100644
index 0000000..27312b8
--- /dev/null
+++ b/tests/lib/isolate/isolate_run_test.dart
@@ -0,0 +1,115 @@
+// Copyright (c) 2022, the Dart project authors.  Please see the AUTHORS file
+// for details. All rights reserved. Use of this source code is governed by a
+// BSD-style license that can be found in the LICENSE file.
+
+import 'dart:isolate';
+import 'dart:async';
+import 'package:async_helper/async_helper.dart';
+import 'package:expect/expect.dart';
+
+void main() async {
+  asyncStart();
+  // Sending result back.
+  await testValue();
+  await testAsyncValue();
+  // Sending error from computation back.
+  await testError();
+  await testAsyncError();
+  // Sending uncaught async error back.
+  await testUncaughtError();
+  // Not sending anything back before isolate dies.
+  await testIsolateHangs();
+  await testIsolateKilled();
+  await testIsolateExits();
+  asyncEnd();
+}
+
+final StackTrace stack = StackTrace.fromString("Known Stacktrace");
+final ArgumentError error = ArgumentError.value(42, "name");
+
+var variable = 0;
+
+Future<void> testValue() async {
+  var value = await Isolate.run<int>(() {
+    variable = 1; // Changed in other isolate!
+    Expect.equals(1, variable);
+    return 42;
+  });
+  Expect.equals(42, value);
+  Expect.equals(0, variable);
+}
+
+Future<void> testAsyncValue() async {
+  var value = await Isolate.run<int>(() async {
+    variable = 1;
+    return 42;
+  });
+  Expect.equals(42, value);
+  Expect.equals(0, variable);
+}
+
+Future<void> testError() async {
+  var e = await asyncExpectThrows<ArgumentError>(Isolate.run<int>(() {
+    variable = 1;
+    Error.throwWithStackTrace(error, stack);
+  }));
+  Expect.equals(42, e.invalidValue);
+  Expect.equals("name", e.name);
+  Expect.equals(0, variable);
+}
+
+Future<void> testAsyncError() async {
+  var e = await asyncExpectThrows<ArgumentError>(Isolate.run<int>(() async {
+    variable = 1;
+    Error.throwWithStackTrace(error, stack);
+  }));
+  Expect.equals(42, e.invalidValue);
+  Expect.equals("name", e.name);
+  Expect.equals(0, variable);
+}
+
+Future<void> testUncaughtError() async {
+  var e = await asyncExpectThrows<RemoteError>(Isolate.run<int>(() async {
+    variable = 1;
+    unawaited(Future.error(error, stack)); // Uncaught error
+    await Completer().future; // Never completes.
+    return -1;
+  }));
+
+  Expect.type<RemoteError>(e);
+  Expect.equals(error.toString(), e.toString());
+  Expect.equals(0, variable);
+}
+
+Future<void> testIsolateHangs() async {
+  var e = await asyncExpectThrows<RemoteError>(Isolate.run<int>(() async {
+    variable = 1;
+    await Completer<Never>().future; // Never completes.
+    // Isolate should end while hanging here, because its event loop is empty.
+  }));
+  Expect.type<RemoteError>(e);
+  Expect.equals("Computation ended without result", e.toString());
+  Expect.equals(0, variable);
+}
+
+Future<void> testIsolateKilled() async {
+  var e = await asyncExpectThrows<RemoteError>(Isolate.run<int>(() async {
+    variable = 1;
+    Isolate.current.kill(); // Send kill request.
+    await Completer<Never>().future; // Never completes.
+    // Isolate should get killed while hanging here.
+  }));
+  Expect.type<RemoteError>(e);
+  Expect.equals("Computation ended without result", e.toString());
+  Expect.equals(0, variable);
+}
+
+Future<void> testIsolateExits() async {
+  var e = await asyncExpectThrows<RemoteError>(Isolate.run<int>(() async {
+    variable = 1;
+    Isolate.exit(); // Dies here without sending anything back.
+  }));
+  Expect.type<RemoteError>(e);
+  Expect.equals("Computation ended without result", e.toString());
+  Expect.equals(0, variable);
+}
diff --git a/tests/lib_2/isolate/isolate_run_test.dart b/tests/lib_2/isolate/isolate_run_test.dart
new file mode 100644
index 0000000..d39c83d
--- /dev/null
+++ b/tests/lib_2/isolate/isolate_run_test.dart
@@ -0,0 +1,117 @@
+// Copyright (c) 2022, the Dart project authors.  Please see the AUTHORS file
+// for details. All rights reserved. Use of this source code is governed by a
+// BSD-style license that can be found in the LICENSE file.
+
+// @dart = 2.9
+
+import 'dart:isolate';
+import 'dart:async';
+import 'package:async_helper/async_helper.dart';
+import 'package:expect/expect.dart';
+
+void main() async {
+  asyncStart();
+  // Sending result back.
+  await testValue();
+  await testAsyncValue();
+  // Sending error from computation back.
+  await testError();
+  await testAsyncError();
+  // Sending uncaught async error back.
+  await testUncaughtError();
+  // Not sending anything back before isolate dies.
+  await testIsolateHangs();
+  await testIsolateKilled();
+  await testIsolateExits();
+  asyncEnd();
+}
+
+final StackTrace stack = StackTrace.fromString("Known Stacktrace");
+final ArgumentError error = ArgumentError.value(42, "name");
+
+var variable = 0;
+
+Future<void> testValue() async {
+  var value = await Isolate.run<int>(() {
+    variable = 1; // Changed in other isolate!
+    Expect.equals(1, variable);
+    return 42;
+  });
+  Expect.equals(42, value);
+  Expect.equals(0, variable);
+}
+
+Future<void> testAsyncValue() async {
+  var value = await Isolate.run<int>(() async {
+    variable = 1;
+    return 42;
+  });
+  Expect.equals(42, value);
+  Expect.equals(0, variable);
+}
+
+Future<void> testError() async {
+  var e = await asyncExpectThrows<ArgumentError>(Isolate.run<int>(() {
+    variable = 1;
+    Error.throwWithStackTrace(error, stack);
+  }));
+  Expect.equals(42, e.invalidValue);
+  Expect.equals("name", e.name);
+  Expect.equals(0, variable);
+}
+
+Future<void> testAsyncError() async {
+  var e = await asyncExpectThrows<ArgumentError>(Isolate.run<int>(() async {
+    variable = 1;
+    Error.throwWithStackTrace(error, stack);
+  }));
+  Expect.equals(42, e.invalidValue);
+  Expect.equals("name", e.name);
+  Expect.equals(0, variable);
+}
+
+Future<void> testUncaughtError() async {
+  var e = await asyncExpectThrows<RemoteError>(Isolate.run<int>(() async {
+    variable = 1;
+    unawaited(Future.error(error, stack)); // Uncaught error
+    await Completer().future; // Never completes.
+    return -1;
+  }));
+
+  Expect.type<RemoteError>(e);
+  Expect.equals(error.toString(), e.toString());
+  Expect.equals(0, variable);
+}
+
+Future<void> testIsolateHangs() async {
+  var e = await asyncExpectThrows<RemoteError>(Isolate.run<int>(() async {
+    variable = 1;
+    await Completer<Never>().future; // Never completes.
+    // Isolate should end while hanging here, because its event loop is empty.
+  }));
+  Expect.type<RemoteError>(e);
+  Expect.equals("Computation ended without result", e.toString());
+  Expect.equals(0, variable);
+}
+
+Future<void> testIsolateKilled() async {
+  var e = await asyncExpectThrows<RemoteError>(Isolate.run<int>(() async {
+    variable = 1;
+    Isolate.current.kill(); // Send kill request.
+    await Completer<Never>().future; // Never completes.
+    // Isolate should get killed while hanging here.
+  }));
+  Expect.type<RemoteError>(e);
+  Expect.equals("Computation ended without result", e.toString());
+  Expect.equals(0, variable);
+}
+
+Future<void> testIsolateExits() async {
+  var e = await asyncExpectThrows<RemoteError>(Isolate.run<int>(() async {
+    variable = 1;
+    Isolate.exit(); // Dies here without sending anything back.
+  }));
+  Expect.type<RemoteError>(e);
+  Expect.equals("Computation ended without result", e.toString());
+  Expect.equals(0, variable);
+}